Trinitrotoluenum (TNT).

TRINITROTOLUENUM
(Trinitrotoluene or trotyl)
Toxic symptoms of the workers in the factories of the explosive, collected by C. Wesselhoeft in 1926.

Pathogenesis

MENTAL SYMPTOMS

1-    Apathy অনীহা, (Cinchonium, Gels, Hell, Ph-ac, Phos)

 Indifference ঔদাসীন্য, (Alumina, anac, apis, calc, carbo-v, china, con, crot-c, gels, hell, lil-t, mez, nat-c, nat-m, nat-p, NV, onos, op, ph-ac, phos, plat, puls, sep, staph, thyr)  Sadness, depression বিষণ্ণতা with crying easily. Aversion to company.
2- Mental torpor বোধশক্তির জড়ত্ব . Slowness. Delirium  প্রলাপবিকার. Coma  অচেতনাবস্থা

Mind  of Zinc .--Weak memory. Very sensitive to noise. Averse to work, to talk. Child repeats everything said to it. Fears arrest on account of a supposed crime. Melancholia. Lethargic, stupid. Paresis. আংশিক পক্ষাঘাত

GENERAL SYMPTOMS

3 -  of trinitrotoluene toxic action on red blood cells causes, in principle, a change in hemoglobin makes the red cells lose much of their oxygen-carrying capacity to the cells, which enter by anoxemia anoxia, observing corresponding symptomatology: extreme fatigue  প্রচণ্ড শারীরিক ও মানসিক ক্লান্তি , shortness of breath, dizziness  মাথা ঘোরা,  fainting, palpitations, cramps, cyanosis, and so on. The destruction of red blood cells causes anemia and a straight jaundice that resulting from cell destruction. In later stages of intoxication, you get to aplastic anemia and toxic jaundice, and by the action on the bone marrow and liver cells, so its therapeutic indication appears in severe anemia and hemolytic jaundice with the picture described above.

Zinc

The provings picture cerebral depression. The word "fag" covers a large part of zinc action. Marked anæmia with profound prostration. It causes a decrease in the number, and destruction of red blood corpuscles. Repercussed eruptive diseases. In chronic diseases with brain and spinal symptoms, trembling, convulsive twitching and fidgety feet are guiding symptoms.

Tissues are worn out faster than they are repaired. Poisoning from suppressed eruptions or discharges. The nervous symptoms of most importance. Defective vitality. Impending brain paralysis. Period of depression in disease.

4 -  The tendency to bleeding, particularly in the form of epistaxis and bruising of the skin.
5 - Fainting, seizures.
6 -  Worse by alcohol and tea.

Zinc.  Cannot stand smallest quantity of wine. . Headache from the smallest quantity of wine

  LABORATORY findings - blood - oxygen - decreased,

            - erythrocytes – decreased

            - ANEMIA – pernicious

            - Hemolytic jaundice

Desire and aversion
7- Grand aversion to tea.

SPECIFIC SYMPTOMS

8- Frontal headache & Dizziness.
9- Nose stuffed feeling dry. Coryza with sneezing.
10-  Face very dark or cyanotic, pale, jaundiced.
11-Taste bitter. Intense thirst

12. Acid regurgitation. Heartburn. Nausea and vomiting.  Zinc  Stomach.-- Hiccough, nausea, vomiting of bitter mucus. Burning in stomach, heartburn from sweet things. Cannot stand smallest quantity of wine. Ravenous hunger about 11 am (Sulph). Great greediness when eating;
13- Constipation followed by diarrhea, abdominal cramps.
14- sudden desire to urinate, burning during urination.
Incontinence ( Inability to prevent escape মূত্র ধারনে অক্ষম) or retention (Inability to escape মূত্র ত্যাগে অক্ষম) of urine which is dark.

Zinc. Urine.--Can only void urine when sitting bent backwards. Hysterical retention. Involuntary urination when walking, coughing or sneezing.
15- Heavy feeling in the chest, suffocating him. Burning in the trachea
Dyspnea. Dry cough and whooping, followed by expectoration of mucus plugs.
Palpitations

16- Tachycardia or bradycardia with intermittent pulse.
17 -  Pain and fatigue in the hollow Popliteal fossa. Yellow hands.   Zinc. Extremities.--Lameness, weakness, trembling and twitching of various muscles.  Feet in continued motion; cannot keep still.

Soles of feet sensitive
18 - Dermatitis. Erythema nodosum. Vesicles. Itching and burning. Purpura.
Ecchymosis. Zinc. Eczema, especially in the anæmic and neurotic. Itching of thighs and hollow of knees. Retrocession of eruptions

Relationship.

     Compare: ZINC.; PHOS.; CINA; ARS.; PLUMBUM.

Dose.

     Thirtieth potency has been used with success.